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GDNF 神經(jīng)膠質(zhì)細(xì)胞源性的神經(jīng)營(yíng)養(yǎng)因子 G-010/050/250
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產(chǎn)品型號(hào):
G-010/050/250
產(chǎn)品報(bào)價(jià):
產(chǎn)品特點(diǎn):
產(chǎn)品名稱:GDNF 神經(jīng)膠質(zhì)細(xì)胞源性的神經(jīng)營(yíng)養(yǎng)因子
產(chǎn)品編號(hào):G-010/050/250
品牌;StemRD
廠家:StemRD
產(chǎn)品規(guī)格:10/50/250ug
儲(chǔ)存條件:-80℃
到貨時(shí)間:2-5天
  G-010/050/250GDNF 神經(jīng)膠質(zhì)細(xì)胞源性的神經(jīng)營(yíng)養(yǎng)因子 G-010/050/250的詳細(xì)資料:

產(chǎn)品信息

Glial Cell Line-derived Neurotrophic Factor (GDNF) is a disulfide-linked homodimeric glycoprotein. Itis a neurotrophic factor structurally belonging to the TGF-beta super family. The GDNF precursor encodes a 211 amino acid residue prepro-peptide that is processed pro-teolytically to a dimeric mature protein consisting of two 134 amino acid residue subunits.
StemRD's GDNF is made in human 293 cells which renders natural dimerization and human-specific post-translational modifications. We purified this product through a series of chromatography to near homogeneity.

Purity:
Greater than 95% by SDS-PAGE under reducing conditions and visualized by silver staining.

Biological Activity:
The activity was determined by using a Elk-1 luciferase reporter gene assay in 293 cells cotransfected with cRET receptor (Worby, et al. Glial Cell Line-derived Neurotrophic Factor Signals through the RET Receptor and Activates Mitogen-activated Protein Kinase. J Biol Chem. 1996; 271:23619). The EC50ranges from 1 - 10 ng/ml.

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